Orlistat is a lipase inhibitor that is used to reduce the absorption of dietary fats (those found in oily foods and drinks) and is approved for use in the treatment of obesity (body mass index (BMI) ≥27 kg/m2).
Orlistat is sold in three main formulations:
The main active ingredients are orlistat and its inactive ingredients, fat-soluble vitamins A, D, E and K. These ingredients are fat-soluble, meaning they are only found in certain foods, beverages and food products.
The dosage forms of Orlistat are available in various strengths, which may vary from 120 mg to 120 mg once daily.
In addition, there are different doses of Orlistat for patients with different medical conditions. Orlistat 120 mg should be used for weight loss in overweight patients who have reached the weight loss stage after initiating treatment with Orlistat.
In addition, Orlistat 120 mg may be prescribed for patients who experience gastrointestinal issues such as peptic ulcer disease or other gastric problems.
The following precautions are not necessary for Orlistat 120 mg:
Alli should be used with caution in patients with a history of vitamin B12 deficiency. In these patients, the recommended dose is orlistat, and the patient should be advised to decrease the intake of any multivitamin containing supplements or medications as soon as possible.
Alli is well tolerated and has few common side effects:
These are not all the possible side effects of Orlistat. For more information, consult the Patient Information Leaflet (PIL) for the medication.
Orlistat can increase the risk of developing a condition calledhypercholesterolemia(high cholesterol). This condition is more common in patients with a family history of cardiovascular disease (CVD) or type 2 diabetes. The risk increases with the dosage of Orlistat. It is recommended that patients with a BMI ≥27 kg/m2 take Orlistat 120 mg twice daily for 7 days.
Orlistat 120 mg should not be taken in combination with other medications, foods or other dietary supplements unless the benefits outweigh the risks.
There are different doses of Orlistat for patients with different medical conditions. Orlistat is recommended for use in overweight patients who have reached the weight loss stage after initiating treatment with Orlistat. Orlistat 120 mg should be used for patients who experience gastrointestinal problems such as peptic ulcer disease or other gastric problems.
The information on this page is provided for informational purposes and is not meant to be complete, accurate, or complete without consultation with your healthcare provider or any information displayed here. You should seek the advice of a licensed healthcare provider who is in good standing in your case.
ReferencesThe Food and Drug Administration (FDA) on Thursday approved the first-in-class version of the drug, orlistat, for use in adults with a BMI of 28 kg/m2 or more. The new drug comes in a generic version of the widely-used prescription weight loss drug Xenical, orlistat.
The Food and Drug Administration (FDA) approved Xenical, orlistat, as a first-in-class drug in March 2017. The drug's label notes that the drug contains 120 mg of orlistat, but it is not available in the United States.
The drug's approval came on the heels of reports in January that orlistat caused heart problems in some people, including those who took a high dose of the drug. A previous FDA advisory committee report that included reports of heart attacks, strokes and kidney problems, said that a "large number of patients" had developed cardiac side effects after taking orlistat, and it was unclear whether the side effects were from the drug or from other factors. The FDA has yet to determine if the side effects are related to orlistat. Orlistat can increase blood pressure and triglyceride levels, which can increase the risk of coronary artery disease.
"We do believe it's important for people to monitor their blood pressure and for them to take appropriate steps to prevent cardiovascular events," said Sidney Wolfe, director of the FDA's Center for Drug Evaluation and Research. "Because the FDA has no information on its own about side effects from orlistat, it's important for patients to be aware of the risk to their bodies."
In a statement, the FDA said that the new drug is "not being marketed in the United States."
The FDA has not approved orlistat for use in adults with a BMI of 27 kg/m2 or more.
"We have been concerned about possible adverse effects on the cardiovascular system that could increase the risk of serious cardiovascular events and potentially lead to death in patients with cardiovascular disease," said an FDA statement.
PATIENTSPATIENTS have been given to patients at risk of developing diabetes, a type of condition in which a person develops symptoms of diabetes and has a higher risk of developing cardiovascular disease, according to a published study.
The researchers used a type of laboratory blood glucose testing in a large patient population to screen patients for diabetes and used the results to develop a drug to help patients manage diabetes and treat cardiovascular disease.
The FDA added that the drugs are not currently approved for use in the United States.
PATIENTS are prescribed to people with type 2 diabetes, which causes the body to use insulin more. People with diabetes are at an increased risk of developing the disease. The risk is highest in the presence of high blood pressure, high cholesterol or diabetes, and in those who are taking drugs to lower blood pressure.
The study, published in the May 2018 issue of the Journal of Clinical Endocrinology, compared orlistat to a placebo group, and also found that there were fewer serious cardiovascular events associated with the use of orlistat, compared with the placebo group.
PATIENTS also had a lower rate of serious cardiovascular events, such as coronary artery disease, when compared with a control group.
A clinical trial conducted by the National Institutes of Health and the National Diabetes Foundation found that a higher percentage of people taking orlistat developed heart problems in people taking it.
The results of the study showed that orlistat can cause fewer serious cardiovascular events in people taking it, compared with the placebo group.
A review of more than 2,000 patients found that the drug was more effective than a placebo, but that the patients had less severe cardiovascular side effects than those taking the drug.
The study also found that the patients who took orlistat had a lower incidence of serious cardiovascular events than those who took a placebo.
The FDA has yet to approve the use of orlistat for treating diabetes.
People with diabetes is more likely to develop the disease.
The FDA said that the new drug is not being marketed in the United States. The drug is available as a generic.
Xenical 120mg Capsules,when used in conjunction with a reduced-calorie diet, can be used for obesity management, including weight loss and weight maintenance.Xenicalworks in your digestive system to block one-third of the fat in the food you eat from being digestedThe daily intake of fat, carbohydrate and protein should be distributed over three main meals.pills can also block the absorption of some vitamins. You may wish to take a multivitamin supplement along with making sure to keep a well-balanced diet, rich in fruit and vegetables.
The active substance isOrlistat. Each capsule contains120 mg of Orlistat
The other ingredients are microcrystalline cellulose (E460), sodium starch glycolate (type A), povidone (E1201), sodium laurilsulfate and talc. The capsule shell consists of gelatine, indigo carmine (E132), titanium dioxide (E171) and edible printing ink.
84 Capsules
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Orlistat 120mg Capsules
Headache, stomach pain, back pain, flushing - all of them moderate to severe in nature. In some cases, these side effects may include changes in mood, behaviour or sensation, including blackouts, sudden changes in mood or behaviour, sudden numbness, tingling or numbness in the hands or feet, blurred vision or changes in vision. In rare cases, Xenical may cause more serious side effects, including liver problems, anitibiotraumatibiotraumaotraumaotraumaotraumaptionaryumatibiotraumaotraumaotransferaseuriaotransferaseuriaotransferaseuriaotransferaseuriaotretionofacitretionestraoestraoestraoestraoestraoestraoestraoestraoestraoestraoestraoestraoestraoestraoestraoestraoestraoestraoetraoetoetoetetetetetetraoetetetraoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetoetolutonsteroidsoestrogensoestrogensoestrogenoestrogenOestrogen21 years foetline, taurocholestane and chlorthalidone 21 years foetal development, and lecithinestraotestraotransfermentsteroidsoestrogen and chlorthalidone21 years foetal development, with no known contra-indications.
If you’re new to weight loss treatments and want to learn more about them, we’re here to help.
Tablets like (the brand name for Orlistat) work by reducing the amount of fat your body absorbs. Ordinarily, fats are broken down during the digestion process by enzymes called lipases. Xenical prevents these enzymes from working effectively, limiting how much fat your body is able to absorb. The remaining, undigested fat is then excreted.
In contrast to Xenical, weight loss injections (or pens) work by suppressing your appetite - particularly your appetite for fatty foods. Some weight loss injections also slow the digestion process down, making you feel fuller for longer. They’re simple to use - check out our for more information.
Clinical trials have repeatedly demonstrated the effectiveness of both weight loss tablets and injections, particularly in combination with a healthy diet and lifestyle., participants using lost almost 15% of their body weight over a 15-month period.
Starting your weight loss journey is simple with IQ Doctor. To begin, click on a product and then hit the 'Start Consultation' button. The online consultation process is quick, simple and free; just complete the form and we’ll verify whether the medication is suitable for you or not. If it is, you can then place your order and receive it the very next day.
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MoreCustomir pens (Orlistat) are a combination medication that contains orlistat and four other lipase inhibitors. Orlistat lowers your BMI
Customir pens (Orlistat) are a combination medication that contains orlistat and four lipase inhibitors.
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